DDR biomarker and PARP/ATR inhibitor response pipeline. Full GDSC v17 mutations + CNV + MSI + tissue context. POC: Talazoparib HRD Spearman ρ=+0.12 (p=3e-4, n=912); per-drug CV AUC 0.68–0.77.
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Updated
Apr 29, 2026 - Python
DDR biomarker and PARP/ATR inhibitor response pipeline. Full GDSC v17 mutations + CNV + MSI + tissue context. POC: Talazoparib HRD Spearman ρ=+0.12 (p=3e-4, n=912); per-drug CV AUC 0.68–0.77.
BiPar Sciences was a Brisbane, California biopharmaceutical company developing a tumor-selective class of PARP (poly ADP-ribose polymerase) inhibitors for cancer therapy. Its lead candidate, BSI-201 (iniparib), was in mid-stage trials for advanced breast, ovarian, and other tumors.
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