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docs: clarify ASCN CCF and Clonal column UI display behavior in File-Formats.md#11994

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copilot/compare-open-prs-clonal
Mar 13, 2026
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docs: clarify ASCN CCF and Clonal column UI display behavior in File-Formats.md#11994
inodb merged 3 commits intomasterfrom
copilot/compare-open-prs-clonal

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Copilot AI commented Feb 26, 2026

Multiple frontend PRs (#5386, #5396, #5399, #5405) all target the same two UI changes in the patient view mutation table: renaming the "Clonality" column to "Clonal" and displaying CCF as a plain number instead of a bar chart for single-sample patients. The backend documentation did not reflect this display behavior.

Changes

  • ASCN.CCF_EXPECTED_COPIES: added that it renders as a plain number for single-sample patients and as a bar chart for multi-sample patients
  • ASCN.CLONAL: added that it renders as a "Clonal" boolean column where only "Clonal" values are indicated with a dot (not "Clonality", matching the frontend rename)

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…Formats.md

Co-authored-by: inodb <1334004+inodb@users.noreply.github.com>
Copilot AI changed the title [WIP] Compare open pull requests related to clonal analysis docs: clarify ASCN CCF and Clonal column UI display behavior in File-Formats.md Feb 26, 2026
Copilot AI requested a review from inodb February 26, 2026 20:06
@inodb inodb marked this pull request as ready for review March 13, 2026 20:06
Copilot AI review requested due to automatic review settings March 13, 2026 20:06
@inodb inodb merged commit cd7f191 into master Mar 13, 2026
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Pull request overview

Updates the mutation file-format documentation for allele-specific copy number (ASCN) namespace columns, adding clarifications about how certain ASCN fields are shown in the patient view mutation table.

Changes:

  • Expanded the description of ASCN.CCF_EXPECTED_COPIES to include patient-view display behavior for single- vs multi-sample patients.
  • Expanded the description of ASCN.CLONAL to include how it appears as a boolean-style “Clonal” indicator in the patient view mutation table.

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42. **ASCN.ASCN_METHOD (Optional)**: Method used to obtain ASCN data e.g "FACETS".
43. **ASCN.CCF_EXPECTED_COPIES (Optional)**: Cancer-cell fraction if mutation exists on major allele.
43. **ASCN.CCF_EXPECTED_COPIES (Optional)**: Cancer-cell fraction if mutation exists on major allele. Displayed as a plain number for single-sample patients or as a bar chart for multi-sample patients in the patient view mutation table.
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3 participants