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_data/WP3981-datanodes.tsv

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Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps
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DNA Metabolite chebi:16991 "" wikidata:Q7430 chebi:16991 kegg.compound:C00039
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PIP3 Metabolite chebi:16618 "" wikidata:Q28797898 chebi:16618 inchikey:RQQIRMLGKSPXSE-UQPICLANSA-N chemspider:34980938 hmdb:HMDB0004249 kegg.compound:C05981
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PIP3 Metabolite chebi:16618 "" wikidata:Q130305209;wikidata:Q28797898 chebi:16618 inchikey:RQQIRMLGKSPXSE-UQPICLANSA-N chemspider:34980938 hmdb:HMDB0004249 kegg.compound:C05981 lipidmaps:LMGP09010000
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MAP2K1 GeneProduct ensembl:ENSG00000169032 "" ensembl:ENSG00000169032 ncbigene:5604 hgnc.symbol:MAP2K1 uniprot:B4DFY5;uniprot:H3BRW9;uniprot:A4QPA9;uniprot:Q02750
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CREBBP GeneProduct ensembl:ENSG00000005339 "" ensembl:ENSG00000005339 ncbigene:1387 hgnc.symbol:CREBBP uniprot:Q92793;uniprot:I3L466;uniprot:A0A1B0GUU0;uniprot:I3L3I5;uniprot:I3L0Q1;uniprot:I3L293
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NFKB1 GeneProduct ensembl:ENSG00000109320 "" ensembl:ENSG00000109320 ncbigene:4790 hgnc.symbol:NFKB1 uniprot:A0A494C157;uniprot:A0A494C1E9;uniprot:P19838;uniprot:D6RC45;uniprot:D6RH30

_pathways/WP2291.md

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---
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annotations:
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- id: PW:0000610
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parent: disease pathway
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type: Pathway Ontology
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value: urinary bladder cancer pathway
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- id: DOID:11054
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parent: disease of cellular proliferation
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type: Disease Ontology
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parent: disease pathway
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type: Pathway Ontology
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value: cancer pathway
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- id: PW:0000610
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parent: disease pathway
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type: Pathway Ontology
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value: urinary bladder cancer pathway
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authors:
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- Anwesha
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- MaintBot
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description: Example of the Rab27 cluster. The Rab27 cluster is comprised of the two
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RAB27 isoforms (RAB27A and RAB27B), the GEF MADD, the GAP TBC1D10A and 12 effector
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proteins
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last-edited: 2021-05-22
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last-edited: 2025-02-24
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ndex: 3a31e185-8b64-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP2291
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- /instance/WP2291
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- /instance/WP2291_r117696
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revision: r117696
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- /instance/WP2291_r136832
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revision: r136832
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP2291.html

_pathways/WP3969.md

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@@ -29,15 +29,15 @@ description: 'In this proposed model, H19 interacts with macroH2A, and this may
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motility in colorectal cancer. Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264449/ Proteins
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on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3969
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CPTAC Assay Portal]'
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last-edited: 2024-05-11
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last-edited: 2025-02-24
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ndex: e40e8b42-8b68-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP3969
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- /instance/WP3969
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- /instance/WP3969_r129540
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revision: r129540
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- /instance/WP3969_r136829
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revision: r136829
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP3969.html

_pathways/WP3981.md

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---
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annotations:
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- id: DOID:10283
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: prostate cancer
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- id: PW:0000605
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parent: disease pathway
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type: Pathway Ontology
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value: cancer pathway
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- id: DOID:10283
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: prostate cancer
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authors:
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- Khanspers
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- Egonw
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subset of highly downregulated miRNAs (>2-fold) in prostate tumors. Note that some
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targeting miRNAs were removed from the original publication figure for clarity.
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These are represented in supplementary table S3: http://journals.sagepub.com/doi/suppl/10.1177/1535370216681554.'
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last-edited: 2024-05-31
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last-edited: 2025-02-24
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ndex: f4ec52de-8b68-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP3981
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- /instance/WP3981
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- /instance/WP3981_r130804
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- /instance/WP3981_r136827
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revision: r136827
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP3981.html

_pathways/WP5078.md

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---
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annotations:
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- id: PW:0000013
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parent: disease pathway
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type: Pathway Ontology
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value: disease pathway
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- id: CL:0002410
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parent: animal cell
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type: Cell Type Ontology
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value: pancreatic stellate cell
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- id: DOID:1793
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: pancreatic cancer
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- id: CL:0001064
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- id: CL:0000084
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parent: native cell
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type: Cell Type Ontology
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value: malignant cell
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value: T cell
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- id: CL:0000889
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parent: native cell
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type: Cell Type Ontology
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value: myeloid suppressor cell
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- id: CL:0000625
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- id: CL:0000145
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parent: native cell
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type: Cell Type Ontology
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value: CD8-positive, alpha-beta T cell
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- id: PW:0000626
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value: professional antigen presenting cell
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- id: DOID:1793
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: pancreatic cancer
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- id: PW:0000013
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parent: disease pathway
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type: Pathway Ontology
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value: pancreatic cancer pathway
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value: disease pathway
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- id: CL:0000625
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parent: native cell
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type: Cell Type Ontology
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value: CD8-positive, alpha-beta T cell
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- id: PW:0000023
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parent: regulatory pathway
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type: Pathway Ontology
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value: immune response pathway
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- id: CL:0000084
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parent: native cell
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- id: CL:0002410
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parent: animal cell
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type: Cell Type Ontology
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value: T cell
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- id: CL:0000145
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parent: native cell
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value: pancreatic stellate cell
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- id: PW:0000626
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parent: disease pathway
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type: Pathway Ontology
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value: pancreatic cancer pathway
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- id: CL:0001064
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type: Cell Type Ontology
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value: professional antigen presenting cell
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value: malignant cell
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authors:
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- DanaMustafa
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- Mkutmon
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is inhibited by various cellular interactions and secreted factors in the tumor
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microenvironment (TME). Both immune cells and pancreatic cancer cells are able to
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modulate T cell activation.
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last-edited: 2025-02-23
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last-edited: 2025-02-24
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ndex: null
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP5078
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- /instance/WP5078
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- /instance/WP5078_r136810
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- /instance/WP5078_r136826
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP5078.html

_pathways/WP5285.md

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annotations:
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- id: CL:0000815
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- id: PW:0000023
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parent: regulatory pathway
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type: Pathway Ontology
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value: immune response pathway
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- id: PW:0000013
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parent: disease pathway
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type: Pathway Ontology
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value: disease pathway
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- id: CL:0000889
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parent: native cell
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type: Cell Type Ontology
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value: regulatory T cell
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- id: CL:0000775
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parent: animal cell
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type: Cell Type Ontology
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value: neutrophil
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value: myeloid suppressor cell
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- id: CL:0000545
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parent: native cell
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type: Cell Type Ontology
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value: T-helper 1 cell
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- id: PW:0000626
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parent: disease pathway
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type: Pathway Ontology
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value: pancreatic cancer pathway
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- id: DOID:1793
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: pancreatic cancer
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- id: CL:0000057
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- id: CL:0002410
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parent: animal cell
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type: Cell Type Ontology
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value: fibroblast
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- id: PW:0000023
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parent: regulatory pathway
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type: Pathway Ontology
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value: immune response pathway
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- id: CL:0000235
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value: pancreatic stellate cell
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- id: CL:0000546
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parent: native cell
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type: Cell Type Ontology
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value: macrophage
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- id: CL:0002410
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value: T-helper 2 cell
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- id: CL:0000057
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parent: animal cell
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type: Cell Type Ontology
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value: pancreatic stellate cell
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- id: CL:0000899
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value: fibroblast
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- id: CL:0000775
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parent: animal cell
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type: Cell Type Ontology
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value: neutrophil
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- id: CL:0000235
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parent: native cell
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type: Cell Type Ontology
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value: T-helper 17 cell
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- id: PW:0000013
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value: macrophage
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- id: PW:0000626
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parent: disease pathway
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type: Pathway Ontology
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value: disease pathway
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- id: CL:0000546
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value: pancreatic cancer pathway
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- id: CL:0000815
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parent: native cell
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type: Cell Type Ontology
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value: T-helper 2 cell
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- id: CL:0000889
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value: regulatory T cell
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- id: DOID:1793
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parent: disease of cellular proliferation
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type: Disease Ontology
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value: pancreatic cancer
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- id: CL:0000899
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parent: native cell
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type: Cell Type Ontology
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value: myeloid suppressor cell
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value: T-helper 17 cell
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authors:
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- IsabelWassink
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- Mkutmon
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by immune cells can be direct and/or indirect. Used cell name abbreviations: MDSC
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= myeloid-derived suppressor cell, Treg = regulatory T cell, CAF = cancer associated
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fibroblast, PSC = pancreatic stellate cell, Th = CD4+ T helper cell.'
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last-edited: 2024-01-30
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last-edited: 2025-02-24
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ndex: null
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- Homo sapiens
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- /index.php/Pathway:WP5285
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- /instance/WP5285
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- /instance/WP5285_r128268
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- /instance/WP5285_r136834
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revision: r136834
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schema-jsonld:
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'@id': https://wikipathways.github.io/pathways/WP5285.html

assets/img/WP2291/WP2291-thumb.png

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assets/img/WP3969/WP3969-thumb.png

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assets/img/WP3981/WP3981-thumb.png

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assets/img/WP5078/WP5078-thumb.png

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