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Update tsv, md and png files
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‎_data/WP4487-datanodes.tsv‎

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@@ -4,7 +4,6 @@ Gamma-Glu-Cys Metabolite wikidata:Q288236 "" wikidata:Q288236 chebi:17515 in
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GSH Metabolite wikidata:Q116907 "aka glutathione" wikidata:Q116907 chebi:16856 inchikey:RWSXRVCMGQZWBV-WDSKDSINSA-N pubchem.compound:124886;pubchem.compound:25246407 chemspider:111188 hmdb:HMDB0000125 kegg.compound:C00051
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2AB Metabolite wikidata:Q27104317 "aka 2-aminobutyrate" wikidata:Q27104317 chebi:35619;chebi:74359 inchikey:QWCKQJZIFLGMSD-VKHMYHEASA-N pubchem.compound:6971252;pubchem.compound:80283 chemspider:72524 hmdb:HMDB0000452 kegg.compound:C02356 lipidmaps:LMFA01100034
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Gamma-Glu-2AB Metabolite pubchem.compound:78437958 "aka gamma-Glutamyl-2-aminobutyrate" wikidata:Q60020843 chebi:133093 inchikey:FUZOZPRKGAXGOB-UHFFFAOYSA-M pubchem.compound:78437958 chemspider:21232230 hmdb:HMDB0242176
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Ophthalmate Metabolite ttd.drug:Q7098084 "aka ophthalmic acid"
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Ophthalmate Metabolite wikidata:Q7098084 "aka ophthalmic acid" wikidata:Q7098084 chebi:84058 inchikey:JCMUOFQHZLPHQP-BQBZGAKWSA-N pubchem.compound:7018721 chemspider:5381695 hmdb:HMDB0005765 kegg.compound:C21016
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GCS Protein eccode:6.3.2.2 "aka Glutamate Cysteine Ligase (GCL) (EC 6.3.2.2), previously known as gamma-glutamylcysteine synthetase (GCS)"
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GS Protein eccode:6.3.2.3 "aka Glutathione synthetase (GSS)"

‎_data/WP5056-datanodes.tsv‎

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Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps
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L-Hydroxyproline Metabolite kegg.genes:C01157 ""
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NO Metabolite kegg.drug:C00533 ""
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L-Hydroxyproline Metabolite kegg.compound:C01157 "" wikidata:Q27102938 chebi:58419;chebi:18095;chebi:18240 inchikey:PMMYEEVYMWASQN-DMTCNVIQSA-N;inchikey:PMMYEEVYMWASQN-BKLSDQPFSA-N pubchem.compound:5810;pubchem.compound:45266637;pubchem.compound:69248 chemspider:5605;chemspider:62461 hmdb:HMDB0000725 kegg.compound:C01157
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NO Metabolite kegg.compound:C00533 "" wikidata:Q207843 chebi:16480 inchikey:MWUXSHHQAYIFBG-UHFFFAOYSA-N pubchem.compound:145068 chemspider:127983 hmdb:HMDB0003378 kegg.compound:C00533
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Vegfa Protein uniprot:Q00731 "" ensembl:ENSMUSG00000023951 ncbigene:22339 uniprot:F8WH10;uniprot:Q00731;uniprot:F8WH81;uniprot:E9Q4N8;uniprot:E9Q4N9
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PDRN Protein uniprot:P37913 "Polydeoxyribonucleotide (PDRN)</br>Protein-ID might be incorrect, as the manuscript does not specify the compound for treatment"
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Nos3 Protein uniprot:P70313 "" ensembl:ENSMUSG00000028978 ncbigene:18127 uniprot:E9Q9X4;uniprot:P70313

‎_data/WP5074-datanodes.tsv‎

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@@ -7,7 +7,6 @@ DAG Metabolite chebi:18035 "" wikidata:Q161466 chebi:18035 kegg.compound
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Hypothalamus Metabolite chebi:65307 "" wikidata:Q27133780 chebi:65307 inchikey:QMZRMXQCHRPRQD-SAWSQHHPSA-N pubchem.compound:70678690 chemspider:34999260
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Ca²⁺ Metabolite chebi:29108 "" wikidata:Q23905776 chebi:29108 inchikey:BHPQYMZQTOCNFJ-UHFFFAOYSA-N pubchem.compound:271 chemspider:266 hmdb:HMDB0000464 kegg.compound:C00076
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Testosterone Metabolite chebi:17347 "" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002
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LH Metabolite uniprot:P01229 "" ensembl:ENSG00000104826 ncbigene:3972 hgnc.symbol:LHB uniprot:P01229;uniprot:A0A0F7RQE6
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Estrogen Metabolite chebi:50114 "" wikidata:Q277954 chebi:50114
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Testosterone Metabolite chebi:17347 "Estradiol</br>Progesteron" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002
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FSH Metabolite chebi:81569 "" wikidata:Q200774 chebi:81569 kegg.compound:C18184
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PLC Protein :9606 ""
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PKC Protein uniprot:A0A087X0I9 ""
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Neurogenin-1 Protein uniprot:F1T0H3 "" ensembl:ENSG00000181965 ncbigene:4762 hgnc.symbol:NEUROG1 uniprot:Q92886;uniprot:F1T0H3
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LH Protein uniprot:P01229 "" ensembl:ENSG00000104826 ncbigene:3972 hgnc.symbol:LHB uniprot:P01229;uniprot:A0A0F7RQE6
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GNRH Protein ensembl:ENSG00000147437 "" ensembl:ENSG00000147437 ncbigene:2796 hgnc.symbol:GNRH1 uniprot:P01148

‎_data/WP5420-datanodes.tsv‎

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@@ -12,7 +12,7 @@ Zn²⁺ Metabolite chebi:29105 "" wikidata:Q26987394 chebi:29105 inchikey:PT
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phenylethylamine2-phenylethylaminePEA Metabolite chebi:225237 "" wikidata:Q28529712 chebi:225237 inchikey:BHHGXPLMPWCGHP-UHFFFAOYSA-O pubchem.compound:448751
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CARI Metabolite chebi:77657 "" wikidata:Q27147250 chebi:77657 inchikey:XFVULMDJZXYMSG-ZIYNGMLESA-L pubchem.compound:86289309 chemspider:31150352
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PA Metabolite chebi:17405 "4-pyridoxic acid" wikidata:Q27102382 chebi:17405 inchikey:HXACOUQIXZGNBF-UHFFFAOYSA-N pubchem.compound:6723 chemspider:6467 hmdb:HMDB0000017 kegg.compound:C00847
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DAG Metabolite kegg.drug:C00165 ""
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DAG Metabolite kegg.compound:C00165 "" wikidata:Q161466 chebi:18035 kegg.compound:C00165 lipidmaps:LMGL0201
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glycine Metabolite chebi:57305 "" wikidata:Q106345678;wikidata:Q620730 chebi:15428;chebi:57305 inchikey:DHMQDGOQFOQNFH-UHFFFAOYSA-N pubchem.compound:750;pubchem.compound:5257127 chemspider:730 hmdb:HMDB0000123 kegg.compound:C00037
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creatine Metabolite chebi:57947 "" wikidata:Q106345487;wikidata:Q223600 chebi:57947;chebi:16919 inchikey:CVSVTCORWBXHQV-UHFFFAOYSA-N pubchem.compound:586 chemspider:566 hmdb:HMDB0000064 kegg.compound:C00300
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Mn²⁺ Metabolite chebi:29035 "" wikidata:Q27095727 chebi:29035 inchikey:WAEMQWOKJMHJLA-UHFFFAOYSA-N pubchem.compound:27854 chemspider:25916 hmdb:HMDB0001333 kegg.compound:C19610

‎_data/WP5434-datanodes.tsv‎

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Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps
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PIP3 Metabolite kegg.compound:C05981 "" wikidata:Q130305209;wikidata:Q28797898 chebi:16618 inchikey:RQQIRMLGKSPXSE-UQPICLANSA-N chemspider:34980938 hmdb:HMDB0004249 kegg.compound:C05981 lipidmaps:LMGP09010000
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Hydroperoxyl radical Metabolite chembl.compound:C21641 ""
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Hydroperoxylradical Metabolite kegg.compound:C21641 ""
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Cholesterol Metabolite hmdb:HMDB00067 "" wikidata:Q43656 chebi:16113 inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N pubchem.compound:5997 chemspider:5775 hmdb:HMDB0000067 kegg.compound:C00187 lipidmaps:LMST01010001
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cAMP Metabolite chebi:17489 "" wikidata:Q210041 chebi:17489 inchikey:IVOMOUWHDPKRLL-KQYNXXCUSA-N pubchem.compound:6076 chemspider:5851 hmdb:HMDB0000058 kegg.compound:C00575
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PA Metabolite kegg.compound:C00416 "" wikidata:Q66000256 chebi:16337 kegg.compound:C00416

‎_data/WP5497-datanodes.tsv‎

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@@ -7,7 +7,7 @@ Anastrozole Metabolite drugbank:DB01217 "" wikidata:Q419143 chebi:2704 inchi
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Exemestane Metabolite drugbank:DB00990 "" wikidata:Q418819 chebi:4953 inchikey:BFYIZQONLCFLEV-DAELLWKTSA-N pubchem.compound:60198 chemspider:54278 hmdb:HMDB0015125 kegg.compound:C08162
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Tamoxifen Metabolite drugbank:DB00675 "" wikidata:Q412178 chebi:41774 inchikey:NKANXQFJJICGDU-QPLCGJKRSA-N pubchem.compound:2733526 chemspider:2015313 hmdb:HMDB0014813
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Fulvestrant Metabolite drugbank:DB00947 "" wikidata:Q5508491 chebi:31638 inchikey:VWUXBMIQPBEWFH-WCCTWKNTSA-N pubchem.compound:104741 chemspider:94553
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Fangchinoline Metabolite drugbank:132893 ""
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Fangchinoline Metabolite chebi:132893 "" wikidata:Q15410976 chebi:132893 inchikey:IIQSJHUEZBTSAT-VMPREFPWSA-N pubchem.compound:73481 chemspider:66173
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MEKi Metabolite drugbank:DBCAT005740 ""
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Palbociclib Metabolite drugbank:DB09073 "" wikidata:Q15269707 chebi:85993 inchikey:AHJRHEGDXFFMBM-UHFFFAOYSA-N pubchem.compound:5330286 chemspider:4487437 hmdb:HMDB0256084
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Ribociclib Metabolite drugbank:DB11730 "" wikidata:Q27088552 chebi:230905 inchikey:RHXHGRAEPCAFML-UHFFFAOYSA-N pubchem.compound:44631912 chemspider:30798107 hmdb:HMDB0257211

‎_data/WP5599-datanodes.tsv‎

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Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps
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IP3 Metabolite chebi:16595 "" wikidata:Q26998374 chebi:16595 inchikey:MMWCIQZXVOZEGG-XJTPDSDZSA-N pubchem.compound:439456 chemspider:388562 hmdb:HMDB0001498 kegg.compound:C01245
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GABA Metabolite chebi:P14867 ""
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GABA Metabolite chebi:16865 "" wikidata:Q106345483;wikidata:Q210021 chebi:16865;chebi:59888 inchikey:BTCSSZJGUNDROE-UHFFFAOYSA-N pubchem.compound:6992099;pubchem.compound:119 chemspider:116 hmdb:HMDB0000112 kegg.compound:C00334 lipidmaps:LMFA01100039
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Ca²⁺ Metabolite chebi:29108 "" wikidata:Q23905776 chebi:29108 inchikey:BHPQYMZQTOCNFJ-UHFFFAOYSA-N pubchem.compound:271 chemspider:266 hmdb:HMDB0000464 kegg.compound:C00076
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glucose Metabolite chebi:17234 "" wikidata:Q37525 chebi:17234 kegg.compound:C00293
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PIP2 Metabolite chebi:18348 "" wikidata:Q130305193;wikidata:Q28797894 chebi:18348 kegg.compound:C04637 lipidmaps:LMGP08010005

‎_data/WP5601-datanodes.tsv‎

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@@ -6,7 +6,7 @@ cAMP Metabolite chebi:17489 "" wikidata:Q210041 chebi:17489 inchikey:IVOMOUW
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AMP Metabolite chebi:16027 "" wikidata:Q318369;wikidata:Q90529152 chebi:16027 inchikey:UDMBCSSLTHHNCD-KQYNXXCUSA-N pubchem.compound:6083 chemspider:5858 hmdb:HMDB0000045 kegg.compound:C00020
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Arginine Metabolite chebi:16467 "" wikidata:Q173670 chebi:16467 inchikey:ODKSFYDXXFIFQN-BYPYZUCNSA-N pubchem.compound:6322;pubchem.compound:28782 chemspider:6082 hmdb:HMDB0000517 kegg.compound:C00062
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NO Metabolite chebi:16480 "" wikidata:Q207843 chebi:16480 inchikey:MWUXSHHQAYIFBG-UHFFFAOYSA-N pubchem.compound:145068 chemspider:127983 hmdb:HMDB0003378 kegg.compound:C00533
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GTP Metabolite chebi:CGEBI:15996 ""
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GTP Metabolite chebi:15996 "" wikidata:Q392227 chebi:15996 inchikey:XKMLYUALXHKNFT-UUOKFMHZSA-N pubchem.compound:6830;pubchem.compound:135398633 chemspider:6569 hmdb:HMDB0001273 kegg.compound:C00044
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cGMP Metabolite chebi:16356 "" wikidata:Q422511 chebi:16356 inchikey:ZOOGRGPOEVQQDX-UUOKFMHZSA-N pubchem.compound:135398570;pubchem.compound:24316 chemspider:22734 hmdb:HMDB0001314 kegg.compound:C00942
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Ca²⁺ Metabolite chebi:29108 "" wikidata:Q23905776 chebi:29108 inchikey:BHPQYMZQTOCNFJ-UHFFFAOYSA-N pubchem.compound:271 chemspider:266 hmdb:HMDB0000464 kegg.compound:C00076
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ADRA1A GeneProduct ensembl:ENSG00000120907 "'A1' in source" ensembl:ENSG00000120907 ncbigene:148 hgnc.symbol:ADRA1A uniprot:E7EW16;uniprot:B0ZBD3;uniprot:P35348

‎_pathways/WP1531.md‎

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---
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annotations:
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- id: DOID:10609
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type: Disease Ontology
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value: rickets
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- id: CL:0002620
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parent: animal cell
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type: Cell Type Ontology
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: vitamin D metabolic pathway
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- id: CL:1000497
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parent: animal cell
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type: Cell Type Ontology
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value: kidney cell
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- id: CL:0000182
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parent: native cell
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type: Cell Type Ontology
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value: hepatocyte
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- id: DOID:10609
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type: Disease Ontology
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value: rickets
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- id: DOID:10573
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type: Disease Ontology
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value: osteomalacia
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- id: PW:0000135
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: metabolic pathway of cofactors, vitamins, nutrients
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- id: CL:1000497
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parent: animal cell
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type: Cell Type Ontology
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value: kidney cell
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- id: DOID:10573
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type: Disease Ontology
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value: osteomalacia
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authors:
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- Evelo
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- Lribeiro
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growth, and immunity. VDR modulates the expression of genes by forming a heterodimer
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complex with retinoid-X-receptors (RXR). Proteins on this pathway have targeted
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assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP1531).
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last-edited: 2025-12-31
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last-edited: 2026-01-02
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ndex: ee30232e-8b62-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP1531
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- /instance/WP1531
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- /instance/WP1531_r142298
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revision: r142298
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- /instance/WP1531_r142319
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revision: r142319
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP1531.html

‎_pathways/WP1596.md‎

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- link: PMC12309891
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title: 'Astrocyte secretome remodeling under iron deficiency: potential implications
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for brain iron homeostasis (2025)'
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communities: []
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description: Iron is nessisary for all mammalian cells but is also toxic in excess.
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This pathway shows the regulation of iron between a cell and the blood stream.
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last-edited: 2023-04-28
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last-edited: 2026-01-02
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ndex: null
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organisms:
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- Mus musculus
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redirect_from:
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- /index.php/Pathway:WP1596
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- /instance/WP1596
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- /instance/WP1596_r126400
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revision: r126400
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- /instance/WP1596_r142309
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revision: r142309
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP1596.html

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