Quoting @tinumide's feedback on the issues that she faced when trying to set up the devstack on macOS.
When I tried to run vagrant up, virtual box wouldn't load. Allowing oracle applications before running vagrant up fixed this for me. To allow oracle applications go to System Preferences > Security & Privacy and hit the allow button.
I couldn't run vagrant because my Xcode command line tools had been uninstalled. It is worth checking that Xcode command line tools are installed especially after a recent update. I'm not sure why an update would cause Xcode command line tools to be uninstalled in the first place.